Engineering Stroke Solutions – Acandis, Germany

Acandis GmbH is a German, owner-managed medical devices company based in Pforzheim.

We specialise in the development, manufacturing and marketing of products for treatment of neurovascular diseases. Our products are used by interventional neuroradiologists for prevention and treatment of stroke.

We are supporting clinical users with innovative products for the neuro-interventional prevention and treatment of stroke – for the benefit of patients. Our work is focused on user-oriented research and development based on a sound knowledge of process technology – Engineering Stroke Solutions!

Acandis®company building

Treatment of intracranial aneurysms

The term intracranial aneurysm is used to describe the dilations or weak points in the walls of arterial blood vessels. Because of the weaknesses in the vessel walls, there is an increased risk of tears in the blood vessels, or ”ruptures”, of the arteries supplying the blood to the brain. This causes bleeding on the surface of the brain (known as subarachnoid haemorrhages) and/or in the brain (known as a brain haemorrhage/ intracerebral bleed­ing) – a life-threatening condition for the patient concerned.

It is therefore vital to be able to recognise and seal off aneurysms that are at risk of rupture. The closure of aneurysms, on an acute or preventive basis, in interventional neuroradiology is performed using minimally invasive, endovascular techniques.

Acandis® offers the following products for the treatment of intracranial aneurysms

Treatment of ischaemic strokes

The term ischaemic stroke is generally used to describe the closure of large cerebral arteries by a blood clot, or ”thrombus”.  This kind of vessel occlusion leads to a reduction in the blood flow and thus to an insufficient supply of oxygen to the area of the brain affected. Longer lasting occlusions can cause irreversible damage to the brain cells – a cerebral infarction.

It is thus vital to restore the flow of blood to the affected area of the brain by removing the clot as quickly as possible.

In addition to drug treatment, mechanical thrombectomy has proved a successful form of treatment.

Acandis® offers the following products for the treatment of ischemic strokes:

Treatment of intracranial stenosis

An intracranial stenosis is a narrowing of the arteries supplying blood to the brain, which is generally caused by arteriosclerosis – a systemic disease leading to deposits of blood lipids, clots, connective tissue and lime.

If it is symptomatic and untreated, an intracranial stenosis presents a very high stroke risk and it should therefore be treated as a matter of urgency.

Alongside drug therapy, intracranial stenosis are treated in interventional neuroradiology by minimally invasive vessel expansion using a balloon catheter (percutaneous transluminal angioplasty – PTA). This treatment is supported if necessary by the implantation of a stent.

Acandis® offers the following products for the treatment of intracranial stenosis treatment:

Catheters

In interventional neuroradiology, various diseases of the blood vessels are treated using minimally invasive, endovascular techniques. By puncturing the artery in the groin, various miniaturised instruments and implants can be navigated into the target region in the brain by using different catheters.

A distinction is made here, for example, between guide catheters, intermediate catheters, microcatheters and balloon catheters, which are used in different combinations depending on the type of therapy.

The Acandis® product portfolio covers the following catheters:

Note: Magnetic Resonance Imaging (MRI) Information

Non-clinical tests have shown that the Acandis implant is suitable for MR-examination. After implantation, patients can be safely scanned with a static magnetic field of 3 Tesla.
The MR imaging quality may be affected if the implant is located in the area of interest. Optimisation of the imaging parameters is recommended.

For further information on MRI compatibility please consult the instructions for use of the respective product.

For more information, see the official site of Acandis>>

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